Grape Seed Extract, CAS# 84929-27-1, is a Plant extracts manufactured through plant extraction, available as brown powder. Grape Seed Extract is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As Grape Seed Extract is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Grape Seed Extract for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Grape Seed Extract could have any negative effects on these vulnerable groups. It should be safe to use Grape Seed Extract in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Grape Seed Extract for long period in food for newborns or pregnant.
Though Grape Seed Extract is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
没有健康问题对葡萄籽提取物的报道up to now.
1. The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers.[Eur J Clin Pharmacol. 2013 Nov]
Author: Goey AK, Meijerman I, Beijnen JH, Schellens JH.
2. Grape seed extract attenuates lung parenchyma pathology in ovalbumin-induced mouse asthma model: an ultrastructural study.[Micron. 2012 Oct]
Author: Mahmoud YI.
3. Grape seed extract alleviates high-fat diet-induced obesity and heart dysfunction by preventing cardiac siderosis.[Cardiovasc Toxicol. 2011 Mar]
Author: Charradi K, Sebai H, Elkahoui S, Ben Hassine F, Limam F, Aouani E.
4. Antilisterial effects of gravinol-s grape seed extract at low levels in aqueous media and its potential application as a produce wash.[J Food Prot. 2010 Feb]
Author: Bisha B, Weinsetel N, Brehm-Stecher BF, Mendonca A.
5. Inhibitory effects of grape seed extract on lipases.[Nutrition. 2003 Oct]
Author: Moreno DA, Ilic N, Poulev A, Brasaemle DL, Fried SK, Raskin I.